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The importance of papillary muscle dyssynchrony in predicting the severity of functional mitral regurgitation in patients with non-ischaemic dilated cardiomyopathy: a two-dimensional speckle-tracking echocardiography study
Conclusion DYS-PAP is correlated with functional MR in non-ischaemic DCM patients with sinus rhythm. A DYS-PAP cut-off value of 30 ms is a useful tool to identify patients with moderate-to-severe functional MR. (Source: European Journal of Echocardiography)

Immune responses and therapeutic anti-tumor effects of an experimental DNA vaccine encoding the human papillomavirus type-16 (HPV-16) oncoproteins genetically fused to the herpes virus glycoprotein D (gD).
In conclusion, the present results expand our previous knowledge on the immune modulation properties of the pgD-E7E6E5 vector and demonstrate, for the first time, the strong anti-tumor effects of the DNA vaccine raising promising perspectives regarding the development of immunotherapeutic reagents for the control of HPV-16-associated tumors.

Pillars article: the CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes. Proc. Natl. Acad. Sci. USA 1988. 85: 5190-5194.
Authors: Rudd CE, Trevillyan JM, Dasgupta JD, Wong LL, Schlossman SF PMID: 20724730 [PubMed - in process] (Source: Journal of Immunology)

Pillars Article: The CD4 and CD8 T Cell Surface Antigens are Associated with the Internal Membrane Tyrosine-Protein Kinase p56lck. Cell 1994. 77: 301-308.
Authors: Veillette A, Bookman MA, Horak EM, Bolen JB PMID: 20724731 [PubMed - in process] (Source: Journal of Immunology)

FDA considers dropping Avastin approval, approves five-day emergency contraception pill
The Food and Drug Administration is considering revoking its approval of a last-ditch breast cancer drug over the debate on "medical spending and effectiveness that flared during the battle over health-care reform," The Washington Post reports. "The [FDA] is reviewing the recommendation of influential scientific advisers to revoke

Detection of Anti-HPV11-L1 Antibodies in Immune Sera from Patients Suffering from Recurrent Respiratory Papillomatosis Using ELISA
Viral Immunology Aug 2010, Vol. 23, No. 4: 415-423. (Source: Viral Immunology)

CD4+ T cells against human papillomavirus-18 E7 in patients with high-grade cervical lesions associate with the absence of the virus in the cervix

Survey on administrating human papillomavirus vaccine for cervical cancer prevention
The vast majority of pediatricians and family physicians nationally are offering the human papillomavirus (also called HPV) vaccine, though fewer physicians are strongly encouraging it for 11- to 12-year-old girls as recommended by national guidelines, according to a survey in the September issue of Pediatrics, the journal of

Experimental Diet Pill May Bring ‘Modest’ Weight Loss
Contrave combines an antidepressant with an anti-addiction drug

Pillars Article: Minor H Antigens Introduced on H-2 Different Stimulating Cells Cross-React at the Cytotoxic T Cell Level during In Vivo Priming. J. Immunol. 1976. 117: 2233-2238.
Authors: Bevan MJ PMID: 20660359 [PubMed - in process] (Source: Journal of Immunology)

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